RABGGTB and PTP4A2

Number of citations of the paper that reports this interaction (PubMedID 11447212)
8

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RABGGTB	PTP4A2
Description		Rab geranylgeranyltransferase subunit beta	protein tyrosine phosphatase 4A2
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	Protein Tyrosine Phosphatase Activity Prenylated Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Prenylation Protein Geranylgeranylation	Peptidyl-tyrosine Dephosphorylation
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation	RAB geranylgeranylation
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	Body mass index ( 26426971)
Interacting Genes		21 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA RPS6KA1 SH3GLB1 TAFA1 TMEM25 WDR4	4 interacting genes: ATF7 CNNM1 CNNM3 RABGGTB
Entrez ID		5876	8073
HPRD ID		01532	03348
Ensembl ID		ENSG00000137955	ENSG00000184007
Uniprot IDs		A8KAJ2 P53611 Q6IB63	Q12974
PDB IDs		6J6X 6J74 6J7F 6J7X 6O60	5K22 5K23 5K25 6WUR
Enriched GO Terms of Interacting Partners?
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