RABGGTA and RABGGTB

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RABGGTA	RABGGTB
Description		Rab geranylgeranyltransferase subunit alpha	Rab geranylgeranyltransferase subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Geranylgeranylation	Cellular Protein Modification Process Visual Perception Protein Prenylation Protein Geranylgeranylation
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate	N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: BMPR2 RAB1A RABGGTB	21 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA RPS6KA1 SH3GLB1 TAFA1 TMEM25 WDR4
Entrez ID		5875	5876
HPRD ID		03547	01532
Ensembl ID		ENSG00000100949	ENSG00000137955
Uniprot IDs		Q92696	A8KAJ2 P53611 Q6IB63
PDB IDs			6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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