CASS4 and ZYX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CASS4	ZYX
Description		Cas scaffold protein family member 4	zyxin
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle
	Molecular Function	Protein Tyrosine Kinase Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Tyrosine Kinase Activity Actin Filament Reorganization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma
Pathways
Drugs			Artenimol
Diseases
GWAS		Alzheimer's disease (late onset) ( 30617256 24162737) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Cognitive decline (age-related) ( 28078323) Family history of Alzheimer's disease ( 30617256) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Refractive astigmatism ( 25367360)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		6 interacting genes: ANKS1B CDC42EP2 FHL3 HSF2BP RAE1 ZYX	35 interacting genes: ACTN1 ATXN1 BSPRY CASS4 ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B
Entrez ID		57091	7791
HPRD ID		09842	03592
Ensembl ID		ENSG00000087589	ENSG00000159840
Uniprot IDs		B4DII4 Q9NQ75	Q15942 Q96AF9
PDB IDs		2CRE
Enriched GO Terms of Interacting Partners?
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