ZYX and PHF21A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ZYX	PHF21A
Description		zyxin	PHD finger protein 21A
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle	Histone Deacetylase Complex Nucleoplasm DNA Repair Complex
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways			HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)	Adult body size ( 32376654) Adventurousness ( 30643258) Axial length ( 24144296) Height ( 29782485) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Menarche (age at onset) ( 21102462 25231870) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		35 interacting genes: ACTN1 ATXN1 BSPRY CASS4 ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B	18 interacting genes: BANP EXOSC8 FHL2 FHL3 H3C14 HDAC1 HDAC2 HMG20A HMG20B KDM1A KRT40 L3MBTL3 LPXN NUP62 RCOR1 SP3 TRAF1 ZYX
Entrez ID		7791	51317
HPRD ID		03592	10516
Ensembl ID		ENSG00000159840	ENSG00000135365
Uniprot IDs		Q15942 Q96AF9	Q96BD5
PDB IDs			2PUY 2YQL
Enriched GO Terms of Interacting Partners?
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