PYY and NPY5R

Number of citations of the paper that reports this interaction (PubMedID 12665544)
15

Data Source:
HPRD (in vivo)

		PYY	NPY5R
Description		peptide YY	neuropeptide Y receptor Y5
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity
	Biological Process	Neuropeptide Signaling Pathway Feeding Behavior Intestinal Epithelial Cell Differentiation	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Peptide YY (3-36)
Diseases
GWAS		Blood protein levels ( 30072576) Diverticular disease ( 30177863) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL levels x fish oil supplementation interaction (2df) ( 33760818) Pulse pressure ( 28135244) Response to taxane treatment (placlitaxel) ( 23006423) Triglyceride levels ( 32203549)
Interacting Genes		6 interacting genes: MEP1B NPY1R NPY2R NPY4R NPY5R SGTA	4 interacting genes: NPY NUPR1 PYY RNF181
Entrez ID		5697	4889
HPRD ID		02869	03591
Ensembl ID		ENSG00000131096	ENSG00000164129
Uniprot IDs		P10082	Q15761
PDB IDs		2DEZ 2DF0 2L60 2NA5	2HE6
Enriched GO Terms of Interacting Partners?
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