NPY5R and RNF181

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NPY5R	RNF181
Description		neuropeptide Y receptor Y5	ring finger protein 181
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse	Cytoplasm
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade	Protein Ubiquitination Protein Autoubiquitination
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	E3 ubiquitin ligases ubiquitinate target proteins
Drugs		Peptide YY (3-36)
Diseases
GWAS			Prostate cancer ( 21743467)
Interacting Genes		4 interacting genes: NPY NUPR1 PYY RNF181	22 interacting genes: BCL10 BIRC2 BTG1 CARD11 CLK4 MRPS6 NPY5R PEG10 RBCK1 TRIM24 TRIM8 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U VPS11 ZMYND10
Entrez ID		4889	51255
HPRD ID		03591	14236
Ensembl ID		ENSG00000164129	ENSG00000168894
Uniprot IDs		Q15761	Q9P0P0
PDB IDs		2HE6
Enriched GO Terms of Interacting Partners?
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