NPY5R and NUPR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NPY5R	NUPR1
Description		neuropeptide Y receptor Y5	nuclear protein 1, transcriptional regulator
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Neuron Projection Synapse	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Intercellular Bridge Perinuclear Region Of Cytoplasm
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity
	Biological Process	Positive Regulation Of Acute Inflammatory Response Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Outflow Tract Morphogenesis Cardiac Left Ventricle Morphogenesis G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Aging Negative Regulation Of Glutamate Secretion Negative Regulation Of Synaptic Transmission, GABAergic Eating Behavior Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Cell Proliferation Generation Of Ovulation Cycle Rhythm Positive Regulation Of ERK1 And ERK2 Cascade	Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Regulation Of Catalytic Activity Negative Regulation Of Programmed Necrotic Cell Death Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Peptide YY (3-36)
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Offspring birth weight ( 31043758) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		4 interacting genes: NPY NUPR1 PYY RNF181	17 interacting genes: ABCG8 ALDH1A1 EP300 KNSTRN MAPRE1 MPHOSPH6 MSL1 NPY5R PAXIP1 PTMA RANBP1 RPL41 SEC11A SET STX18 SYNCRIP TUBA4A
Entrez ID		4889	26471
HPRD ID		03591	17814
Ensembl ID		ENSG00000164129	ENSG00000176046
Uniprot IDs		Q15761	A0A024QZC4 O60356
PDB IDs		2HE6
Enriched GO Terms of Interacting Partners?
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