SMCO4 and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMCO4	IL10RA
Description		single-pass membrane protein with coiled-coil domains 4	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Biological_process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis
Pathways			Interleukin-10 signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)	Obesity-related traits ( 23251661)
Interacting Genes		60 interacting genes: AQP6 ATP2A2 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	22 interacting genes: BTRC C1QL4 CDS2 CMTM3 DRD2 HACD1 IL10 IL10RB JAK1 KMT2A MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		56935	3587
HPRD ID		17008	00911
Ensembl ID		ENSG00000166002	ENSG00000110324
Uniprot IDs		A0A024R3A3 Q9NRQ5	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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