SMCO4 and ICAM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMCO4	ICAM3
Description		single-pass membrane protein with coiled-coil domains 4	intercellular adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Signaling Receptor Binding Integrin Binding Protein Binding
	Biological Process	Biological_process	Phagocytosis Cell Adhesion Cell-cell Adhesion
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		60 interacting genes: AQP6 ATP2A2 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	29 interacting genes: APP BRICD5 C3 CALR CD209 CLDN19 CLDN4 CLEC4M EDDM3B EPOR EZR GCC2 ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ PRLR RFX2 RPL18 SEC22A SFTPC SMCO4 SMIM1 TNFRSF1B TSPO USF2 ZBTB16
Entrez ID		56935	3385
HPRD ID		17008	00889
Ensembl ID		ENSG00000166002	ENSG00000076662
Uniprot IDs		A0A024R3A3 Q9NRQ5	A0A024R7C1 K7ERN2 P32942
PDB IDs			1T0P
Enriched GO Terms of Interacting Partners?
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