SMCO4 and HHLA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SMCO4	HHLA2
Description		single-pass membrane protein with coiled-coil domains 4	HERV-H LTR-associating 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cellular_component External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Molecular_function Signaling Receptor Binding Protein Binding
	Biological Process	Biological_process	Regulation Of Cytokine Production Positive Regulation Of Cytokine Production T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)	Regular attendance at a religious group ( 29970889)
Interacting Genes		60 interacting genes: AQP6 ATP2A2 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	14 interacting genes: AQP9 BRICD5 BTNL8 C3orf52 ERMP1 FAM3C NIPAL4 NRM PGA4 RPRM SMCO4 TMEM140 TNMD UNC93B1
Entrez ID		56935	11148
HPRD ID		17008	05082
Ensembl ID		ENSG00000166002	ENSG00000114455
Uniprot IDs		A0A024R3A3 Q9NRQ5	C9J7D0 Q9UM44
PDB IDs
Enriched GO Terms of Interacting Partners?
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