LAPTM4B and CGRRF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LAPTM4B	CGRRF1
Description		lysosomal protein transmembrane 4 beta	cell growth regulator with ring finger domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding Metal Ion Binding
	Biological Process	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) QT interval ( 24952745)	Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)
Interacting Genes		22 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM67 TMEM86B TRARG1	32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1
Entrez ID		55353	10668
HPRD ID		13960	09366
Ensembl ID		ENSG00000104341	ENSG00000100532
Uniprot IDs		Q86VI4	Q99675
PDB IDs			2EA5
Enriched GO Terms of Interacting Partners?
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