CGRRF1 and RHBDD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CGRRF1	RHBDD1
Description		cell growth regulator with ring finger domain 1	rhomboid domain containing 1
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GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding Metal Ion Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth	Apoptotic Process Positive Regulation Of Protein Processing Membrane Protein Intracellular Domain Proteolysis Cellular Response To Unfolded Protein Cellular Response To UV ERAD Pathway Negative Regulation Of Apoptotic Process Post-translational Protein Modification Spermatid Differentiation Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Regulation Of Male Germ Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Kawasaki disease ( 33692975) Pulmonary function ( 17903307)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	19 interacting genes: CGRRF1 CMTM5 CREB3L1 CTSA DAPK1 FBXO25 GYPC LPCAT2 LRRK2 MFHAS1 NSDHL PLEKHB2 RNF5 SEC22B SLC66A2 TGFA TMEM42 TMEM86B TMIE
Entrez ID		10668	84236
HPRD ID		09366	13206
Ensembl ID		ENSG00000100532	ENSG00000144468
Uniprot IDs		Q99675	Q8TEB9
PDB IDs		2EA5	5EPP
Enriched GO Terms of Interacting Partners?
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