LAPTM4B and CTXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LAPTM4B	CTXN3
Description		lysosomal protein transmembrane 4 beta	cortexin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle	Integral Component Of Membrane
	Molecular Function	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) QT interval ( 24952745)	Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		22 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM67 TMEM86B TRARG1	59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12
Entrez ID		55353	613212
HPRD ID		13960	18888
Ensembl ID		ENSG00000104341	ENSG00000205279
Uniprot IDs		Q86VI4	Q4LDR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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