LAPTM4B and ISLR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LAPTM4B	ISLR2
Description		lysosomal protein transmembrane 4 beta	immunoglobulin superfamily containing leucine rich repeat 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization	Positive Regulation Of Axon Extension
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) QT interval ( 24952745)	Blood protein levels ( 30072576 29875488)
Interacting Genes		22 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM67 TMEM86B TRARG1	6 interacting genes: EMP1 LAPTM4B MRAP2 NKG7 STRIT1 UPK1B
Entrez ID		55353	57611
HPRD ID		13960	13865
Ensembl ID		ENSG00000104341	ENSG00000167178
Uniprot IDs		Q86VI4	Q6UXK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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