ADPRS and PRDM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ADPRS	PRDM5
Description		ADP-ribosylserine hydrolase	PR/SET domain 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Nuclear Body Site Of DNA Damage	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Magnesium Ion Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Poly(ADP-ribose) Glycohydrolase Activity Protein Binding O-acetyl-ADP-ribose Deacetylase Activity ADP-ribosylserine Hydrolase Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process	DNA Repair Base-excision Repair, Gap-filling Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of Gene Expression Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor
Pathways		POLB-Dependent Long Patch Base Excision Repair
Drugs
Diseases
GWAS			F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)
Interacting Genes		6 interacting genes: FRA10AC1 HEXD HSPB1 MAP7D1 PRDM5 TNKS	7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1
Entrez ID		54936	11107
HPRD ID		12432	17902
Ensembl ID		ENSG00000116863	ENSG00000138738
Uniprot IDs		B7ZAN4 Q9NX46	Q9NQX1
PDB IDs		2FOZ 2FP0 2G4K 5ZQY 6D36 6D3A
Enriched GO Terms of Interacting Partners?
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