PRDM5 and CLCN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRDM5	CLCN1
Description		PR/SET domain 5	chloride voltage-gated channel 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of Gene Expression Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases
GWAS		F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)
Interacting Genes		7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1	7 interacting genes: AHSA1 APPBP2 CIDEB FAM9B FKBP8 PRDM5 STIP1
Entrez ID		11107	1180
HPRD ID		17902	00320
Ensembl ID		ENSG00000138738	ENSG00000188037
Uniprot IDs		Q9NQX1	P35523
PDB IDs			6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU
Enriched GO Terms of Interacting Partners?
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