PRDM5 and ADPRS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRDM5	ADPRS
Description		PR/SET domain 5	ADP-ribosylserine hydrolase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Nuclear Body Site Of DNA Damage
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Magnesium Ion Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Poly(ADP-ribose) Glycohydrolase Activity Protein Binding O-acetyl-ADP-ribose Deacetylase Activity ADP-ribosylserine Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of Gene Expression Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Methylation Cellular Response To Leukemia Inhibitory Factor	DNA Repair Base-excision Repair, Gap-filling Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation
Pathways			POLB-Dependent Long Patch Base Excision Repair
Drugs
Diseases
GWAS		F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)
Interacting Genes		7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1	6 interacting genes: FRA10AC1 HEXD HSPB1 MAP7D1 PRDM5 TNKS
Entrez ID		11107	54936
HPRD ID		17902	12432
Ensembl ID		ENSG00000138738	ENSG00000116863
Uniprot IDs		Q9NQX1	B7ZAN4 Q9NX46
PDB IDs			2FOZ 2FP0 2G4K 5ZQY 6D36 6D3A
Enriched GO Terms of Interacting Partners?
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