LEPROT and SYNGR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LEPROT	SYNGR1
Description		leptin receptor overlapping transcript	synaptogyrin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Golgi Apparatus Endosome Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding
	Biological Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Protein Localization To Cell Surface	Protein Targeting Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		BMI at adiposity peak ( 31840077)	Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 32723749 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Systemic lupus erythematosus ( 33272962) Ulcerative colitis ( 28067908) vWF levels ( 30586737)
Interacting Genes		11 interacting genes: AQP6 C1GALT1 GJA5 PLPPR1 SLC7A1 SMO SYNGR1 TMEM120A TMEM50A TMX2 YIPF1	31 interacting genes: ADORA2A AQP6 CACNA1I CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A
Entrez ID		54741	9145
HPRD ID		13987	06800
Ensembl ID		ENSG00000213625	ENSG00000100321
Uniprot IDs		A0A087X0N2 O15243	O43759
PDB IDs
Enriched GO Terms of Interacting Partners?
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