SYNGR1 and TMEM80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYNGR1	TMEM80
Description		synaptogyrin 1	transmembrane protein 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome	Integral Component Of Membrane Ciliary Transition Zone
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Targeting Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor	Non-motile Cilium Assembly
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 32723749 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Systemic lupus erythematosus ( 33272962) Ulcerative colitis ( 28067908) vWF levels ( 30586737)
Interacting Genes		31 interacting genes: ADORA2A AQP6 CACNA1I CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		9145	283232
HPRD ID		06800	14143
Ensembl ID		ENSG00000100321	ENSG00000177042
Uniprot IDs		O43759	A0A0A0MTU4 B7Z7W9 Q96HE8
PDB IDs
Enriched GO Terms of Interacting Partners?
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