PLEKHA5 and RECQL

		PLEKHA5	RECQL
Description		pleckstrin homology domain containing A5	RecQ like helicase
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Nucleus Nucleoplasm Chromosome Cytoplasm Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding Four-way Junction Helicase Activity ATP Hydrolysis Activity ATP-dependent DNA/DNA Annealing Activity 3'-5' DNA Helicase Activity
	Biological Process	Biological_process Reproductive System Development	Double-strand Break Repair Via Homologous Recombination DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)	Blood protein levels ( 30072576)
Interacting Genes		36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	7 interacting genes: KPNA2 KPNA4 MARK3 NKX2-2 PLEKHA5 RPA1 UBC
Entrez ID		54477	5965
HPRD ID		09684	02762
Ensembl ID		ENSG00000052126	ENSG00000004700
Uniprot IDs		A0A024RAY7 Q9HAU0	A0A024RAV2 P46063
PDB IDs		2DKP	2V1X 2WWY 4U7D 6JTZ
Enriched GO Terms of Interacting Partners?
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