POLE2 and POLE4

Number of citations of the paper that reports this interaction (PubMedID 10801849)
28

Data Source:
HPRD (in vitro)

		POLE2	POLE4
Description		DNA polymerase epsilon 2, accessory subunit	DNA polymerase epsilon 4, accessory subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Epsilon DNA Polymerase Complex Nuclear Body Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Epsilon DNA Polymerase Complex
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA Replication DNA-dependent DNA Replication DNA Repair Error-prone Translesion Synthesis	DNA Biosynthetic Process
Pathways		Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex	Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs		Cladribine	Cladribine
Diseases
GWAS		Trigger finger ( 32740585)	Venous thromboembolism ( 33592630)
Interacting Genes		25 interacting genes: AGFG1 ATOH1 BAIAP2L2 DRD3 EEF1A1 ERG28 EXOSC4 KAT5 MAPRE1 NID2 PARK7 PKM POLE POLE4 PYGL REL SAP18 SAV1 SORBS3 TBX15 TLE1 TRIM27 UBQLN2 ZBED1 ZNF620	11 interacting genes: B4GALT4 EVA1A HSPA13 NFYB POLE POLE2 POLE3 PRKAR1B REG3G SGO1 UBE3A
Entrez ID		5427	56655
HPRD ID		16007	16238
Ensembl ID		ENSG00000100479	ENSG00000115350
Uniprot IDs		P56282	Q9NR33
PDB IDs		2V6Z 5VBN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?