PGD and OS9

		PGD	OS9
Description		phosphogluconate dehydrogenase	OS9 endoplasmic reticulum lectin
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GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane
	Molecular Function	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding	Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Response To Endoplasmic Reticulum Stress Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Pentose phosphate pathway	ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs		Gadopentetic acid Dacarbazine Ketotifen 6-phospho-D-gluconic acid Nicotinamide 8-bromo-adenine dinucleotide phosphate
Diseases
GWAS		Hemoglobin ( 32888494) Hepatocellular carcinoma ( 20676096) Metabolite levels ( 23823483)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 31604244) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		9 interacting genes: ALG5 CDC42 CDK4 GBE1 LINC01554 LSM8 OGT OS9 TERF1	28 interacting genes: ACP1 ACVR1B CPNE6 CREB3 DCSTAMP DYSF EGLN1 EGLN3 EIF6 FAIM2 FOXM1 GLS2 HIF1A HSP90B1 LINC00839 MEP1B P3H3 PGD PTH RBX1 SCN8A SLC22A1 SMAD2 SNRPD2 SREBF2 TRPV4 UVRAG ZNF512B
Entrez ID		5226	10956
HPRD ID		01391	17804
Ensembl ID		ENSG00000142657	ENSG00000135506
Uniprot IDs		B4E2U0 P52209	Q13438
PDB IDs		2JKV 4GWG 4GWK 5UQ9	3AIH
Enriched GO Terms of Interacting Partners?
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