PGD and LSM8

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		PGD	LSM8
Description		phosphogluconate dehydrogenase	LSM8 homolog, U6 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Catabolic Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways		Pentose phosphate pathway	mRNA Splicing - Major Pathway
Drugs		Gadopentetic acid Dacarbazine Ketotifen 6-phospho-D-gluconic acid Nicotinamide 8-bromo-adenine dinucleotide phosphate
Diseases
GWAS		Hemoglobin ( 32888494) Hepatocellular carcinoma ( 20676096) Metabolite levels ( 23823483)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 33627673 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 33082346) Smoking status (current vs never) ( 33082346) Triglyceride levels ( 30108155)
Interacting Genes		9 interacting genes: ALG5 CDC42 CDK4 GBE1 LINC01554 LSM8 OGT OS9 TERF1	49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		5226	51691
HPRD ID		01391	06288
Ensembl ID		ENSG00000142657	ENSG00000128534
Uniprot IDs		B4E2U0 P52209	A4D0W0 O95777
PDB IDs		2JKV 4GWG 4GWK 5UQ9	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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