PAM16 and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PAM16	PGRMC1
Description		presequence translocase associated motor 16	progesterone receptor membrane component 1
Image		No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Ossification Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Apoptotic DNA Fragmentation	Heme Biosynthetic Process
Pathways		Mitochondrial protein import	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Hodgkin's lymphoma ( 34216518)
Interacting Genes		9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1	21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71
Entrez ID		51025	10857
HPRD ID		14798	02338
Ensembl ID		ENSG00000217930	ENSG00000101856
Uniprot IDs		Q9Y3D7	O00264 Q6IB11
PDB IDs			4X8Y
Enriched GO Terms of Interacting Partners?
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