PGRMC1 and MX1

		PGRMC1	MX1
Description		progesterone receptor membrane component 1	MX dynamin like GTPase 1
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GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Microtubule Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Heme Biosynthetic Process	Apoptotic Process Defense Response Signal Transduction Response To Virus Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		Neutrophil degranulation	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)
Interacting Genes		21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623
Entrez ID		10857	4599
HPRD ID		02338	00919
Ensembl ID		ENSG00000101856	ENSG00000157601
Uniprot IDs		O00264 Q6IB11	P20591
PDB IDs		4X8Y	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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