PGRMC1 and DEFB124

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		PGRMC1	DEFB124
Description		progesterone receptor membrane component 1	defensin beta 124
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Extracellular Region
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding
	Biological Process	Heme Biosynthetic Process	I-kappaB Kinase/NF-kappaB Signaling Defense Response To Bacterium Innate Immune Response Cellular Response To Peptidoglycan Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production Positive Regulation Of Monocyte Chemotaxis
Pathways		Neutrophil degranulation	Beta defensins Defensins
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)
Interacting Genes		21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	2 interacting genes: NCK2 PGRMC1
Entrez ID		10857	245937
HPRD ID		02338	18759
Ensembl ID		ENSG00000101856	ENSG00000180383
Uniprot IDs		O00264 Q6IB11	Q8NES8
PDB IDs		4X8Y
Enriched GO Terms of Interacting Partners?
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