PAM16 and BLOC1S2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PAM16	BLOC1S2
Description		presequence translocase associated motor 16	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Ossification Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Apoptotic DNA Fragmentation	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Refractive error ( 32231278)
Interacting Genes		9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1	35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3
Entrez ID		51025	282991
HPRD ID		14798	12526
Ensembl ID		ENSG00000217930	ENSG00000196072
Uniprot IDs		Q9Y3D7	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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