ATP1A3 and PPFIA3

		ATP1A3	PPFIA3
Description		ATPase Na+/K+ transporting subunit alpha 3	PTPRF interacting protein alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Integral Component Of Membrane Axon Organelle Membrane Neuronal Cell Body Membrane Neuronal Cell Body Synapse Photoreceptor Inner Segment Membrane Neuron To Neuron Synapse Extracellular Vesicle	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse
	Molecular Function	Amyloid-beta Binding P-type Sodium:potassium-exchanging Transporter Activity Protein Binding ATP Binding ATP Hydrolysis Activity Metal Ion Binding Chaperone Binding Ion Antiporter Activity Involved In Regulation Of Presynaptic Membrane Potential Steroid Hormone Binding	Protein Binding
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Sodium Ion Export Across Plasma Membrane Regulation Of Resting Membrane Potential Cellular Response To Steroid Hormone Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Proton Transmembrane Transport Response To Glycoside Cellular Response To Amyloid-beta Neuron Projection Maintenance Potassium Ion Import Across Plasma Membrane	Neurotransmitter Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs		Ouabain
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Meat-related diet ( 32066663)	Adult body size ( 32376654) Leukoderma in response to rhododendrol ( 32558222)
Interacting Genes		11 interacting genes: ABCA4 ASH2L ATRX ATXN1 CASP8 DUSP4 LYPD3 PPFIA3 PRKD2 TRIM29 ZNF229	17 interacting genes: ATP1A3 CAST CBY2 DISC1 ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PPP1R13B PTPRD PTPRF PTPRS PTPRU SORBS3 TFIP11
Entrez ID		478	8541
HPRD ID		01666	04393
Ensembl ID		ENSG00000105409	ENSG00000177380
Uniprot IDs		P13637 Q53ES0	O75145
PDB IDs
Enriched GO Terms of Interacting Partners?
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