ATP1A3 and TRIM29

		ATP1A3	TRIM29
Description		ATPase Na+/K+ transporting subunit alpha 3	tripartite motif containing 29
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Integral Component Of Membrane Axon Organelle Membrane Neuronal Cell Body Membrane Neuronal Cell Body Synapse Photoreceptor Inner Segment Membrane Neuron To Neuron Synapse Extracellular Vesicle	Lysosome Adherens Junction
	Molecular Function	Amyloid-beta Binding P-type Sodium:potassium-exchanging Transporter Activity Protein Binding ATP Binding ATP Hydrolysis Activity Metal Ion Binding Chaperone Binding Ion Antiporter Activity Involved In Regulation Of Presynaptic Membrane Potential Steroid Hormone Binding	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Sodium Ion Export Across Plasma Membrane Regulation Of Resting Membrane Potential Cellular Response To Steroid Hormone Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Proton Transmembrane Transport Response To Glycoside Cellular Response To Amyloid-beta Neuron Projection Maintenance Potassium Ion Import Across Plasma Membrane	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Interferon gamma signaling
Drugs		Ouabain
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Meat-related diet ( 32066663)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		11 interacting genes: ABCA4 ASH2L ATRX ATXN1 CASP8 DUSP4 LYPD3 PPFIA3 PRKD2 TRIM29 ZNF229	56 interacting genes: ACTN3 ANKS1A ATM ATP1A3 CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 HNRNPLL IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		478	23650
HPRD ID		01666	10280
Ensembl ID		ENSG00000105409	ENSG00000137699
Uniprot IDs		P13637 Q53ES0	A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs			2CSV
Enriched GO Terms of Interacting Partners?
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