MPZ and PMP22

Number of citations of the paper that reports this interaction (PubMedID 10212299)
21

Data Source:
HPRD (in vitro, in vivo)

		MPZ	PMP22
Description		myelin protein zero	peripheral myelin protein 22
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Myelin Sheath Synapse	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse
	Molecular Function	Structural Molecule Activity	Protein Binding
	Biological Process	Chemical Synaptic Transmission Myelination Negative Regulation Of Apoptotic Process Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Aggregation	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Population Proliferation Negative Regulation Of Neuron Projection Development Cell Differentiation Bleb Assembly Myelin Assembly
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Visceral adipose tissue adjusted for BMI ( 22589738)	Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		6 interacting genes: DEDD HSPA6 PINX1 PMP22 PSMB3 RGS4	59 interacting genes: APOL3 ARL13B ASGR2 ATP6AP2 C16orf54 CANX CD3G CD53 CD69 CEACAM3 CLDN18 CLDN5 CLDN6 CLEC12B CLEC14A CREB3 CREB3L1 DDX52 EBP EDA EMP1 ERGIC3 FAM209A FCGRT FFAR2 GJA8 GPR42 GPR61 GPRC5D IFNGR2 KCNJ6 KCNN4 KLRC1 LMNA MPZ MS4A7 OPRM1 PDZK1IP1 PEX19 PGRMC2 REEP4 SCN3B SDC4 SHISAL1 SLC18A1 SLC38A1 SMIM3 SPACA1 STOM SYT2 TLCD4 TM4SF18 TM4SF19 TMEM139 TMEM14B TMEM30B TMEM31 TMX1 TSPAN12
Entrez ID		4359	5376
HPRD ID		01159	03059
Ensembl ID		ENSG00000158887	ENSG00000109099
Uniprot IDs		A0A5F9ZI26 P25189	A8MU75 Q01453 Q6FH25
PDB IDs		1N2P 3OAI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?