MPP1 and SGSM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPP1	SGSM2
Description		MAGUK p55 scaffold protein 1	small G protein signaling modulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Cytoplasm Melanosome
	Molecular Function	Guanylate Kinase Activity Protein Binding	GTPase Activator Activity Small GTPase Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	Intracellular Protein Transport Late Endosome To Golgi Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity
Pathways		Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)
Interacting Genes		46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	20 interacting genes: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25
Entrez ID		4354	9905
HPRD ID		02370	15284
Ensembl ID		ENSG00000130830	ENSG00000141258
Uniprot IDs		B4E325 Q00013	B9A6J3 O43147
PDB IDs		2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?
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