MPP1 and ABCC4

Number of citations of the paper that reports this interaction (PubMedID 29146910)
9

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MPP1	ABCC4
Description		MAGUK p55 scaffold protein 1	ATP binding cassette subfamily C member 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Dense Granule Membrane External Side Of Apical Plasma Membrane
	Molecular Function	Guanylate Kinase Activity Protein Binding	Guanine Nucleotide Transmembrane Transporter Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity Prostaglandin Transmembrane Transporter Activity Urate Transmembrane Transporter Activity Purine Nucleotide Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity ABC-type Bile Acid Transporter Activity Efflux Transmembrane Transporter Activity P-type Ion Transporter Activity 15-hydroxyprostaglandin Dehydrogenase (NAD+) Activity Glutathione Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	Platelet Degranulation Response To Xenobiotic Stimulus Response To Organonitrogen Compound Response To Organic Cyclic Compound Inorganic Anion Transport Bile Acid And Bile Salt Transport Prostaglandin Transport Urate Transport Prostaglandin Secretion Glutathione Transmembrane Transport Bile Acid Signaling Pathway Xenobiotic Transport Positive Regulation Of Smooth Muscle Cell Proliferation Transmembrane Transport Cilium Assembly CAMP Transport Leukotriene Transport Export Across Plasma Membrane Transport Across Blood-brain Barrier Guanine Nucleotide Transmembrane Transport
Pathways		Sensory processing of sound by outer hair cells of the cochlea	Platelet degranulation ABC-family proteins mediated transport
Drugs			ATP
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Acute post-radiotherapy pain in breast cancer ( 31196165) Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Blood metabolite levels ( 24816252) Breast cancer ( 17903305) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Longevity ( 20834067) Parent of origin effect on language impairment (paternal) ( 24571439) Platelet count ( 22139419 29403010 32888494 27863252) Plateletcrit ( 32888494 27863252) Postherpetic neuralgia ( 33685280) Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer ( 23478653) Serum metabolite levels ( 33031748)
Interacting Genes		46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	6 interacting genes: ERBIN MPP1 PDZK1 SLC9A3R1 SLC9A3R2 SNTA1
Entrez ID		4354	10257
HPRD ID		02370	05583
Ensembl ID		ENSG00000130830	ENSG00000125257
Uniprot IDs		B4E325 Q00013	A8K2Q2 O15439
PDB IDs		2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?
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