Description |
MDM2 proto-oncogene |
casein kinase 2 alpha 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- ATP
- (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
- 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
- Resveratrol
- 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
- Benzamidine
- 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
- Quercetin
- Phosphoaminophosphonic Acid-Adenylate Ester
- Tetrabromo-2-Benzotriazole
- DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
- S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
- Emodin
- 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
- 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
- N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
- 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
- N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
- Dichlororibofuranosylbenzimidazole
- Quinalizarin
- Ellagic acid
- Fostamatinib
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Diseases |
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GWAS |
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Interacting Genes |
261 interacting genes:
ABL1
ABL2
ADRB2
AKAP5
AKT1
ANKRD17
APEX1
APP
AR
ARRB1
ARRB2
ATF4
ATM
ATP2A2
ATRX
AURKA
BAIAP2L1
BRINP1
BTK
BTRC
CANX
CASP2
CASP3
CCAR1
CCNG1
CDC34
CDKN2A
CHEK2
CLSTN1
CLU
COPS5
CREBBP
CSNK2A1
CSNK2A2
CSNK2B
CTBP2
CWC25
DAPK1
DAPK3
DAXX
DDX24
DDX42
DHFR
DLG4
DNAJB4
DYRK2
EGLN3
EID1
EP300
ESR1
EZR
F3
FBXO31
FGFR2
FHL2
FKBP1A
FOS
FOXO1
FOXO3
FOXP3
G3BP2
GADD45A
GCAT
GLIS2
GNL3
GORAB
GRK2
GSK3B
GTF2E2
GYS2
H2BC21
H3-4
HCK
HDAC1
HEY1
HIF1A
HIPK2
HLA-DMB
HMGA2
HMGN1
HNRNPK
HSP90B1
IER3
IGF1R
IRF1
IRF2
JMY
JUN
JUND
KAT2B
KAT5
KPNA1
LMO7
MAGEA2
MAP1LC3A
MAP2
MAPKAPK2
MDM4
MED1
MKRN3
MS4A1
MTBP
MYC
MYD88
MYDGF
NACA
NAT10
NCL
NDUFS1
NGFR
NOLC1
NOP53
NOTCH1
NPIPB3
NPM1
NR3C1
NUCKS1
NUMB
PAK6
PBX1
PBXIP1
PDE4D
PDIA3
PDLIM7
PDS5A
PER2
PGAM2
PHF7
PHLDB3
PIAS1
PJA1
PKM
PLK1
PML
POLE
POT1
PPIB
PPM1D
PPP1R10
PRDM2
PRKN
PSMA3
PSMC5
PSMD10
PSMD4
PSME3
PTK2
RAB8A
RAD23A
RANBP1
RANBP2
RARA
RASSF1
RB1
RBBP6
RBM10
RBM38
RCHY1
RESF1
RIDA
RLIM
RNF10
RNF126
RNF8
RPL11
RPL22
RPL26
RPL36A
RPL4
RPL5
RPS23
RPS27A
RPS3
RPS5
RRM2B
RRP1
RSL1D1
RUVBL2
RYBP
RYR2
S100A1
S100A2
S100A4
S100A6
S100B
SDHC
SENP3
SESN2
SET
SETD7
SETDB1
SHPK
SIRT2
SIRT3
SMARCA2
SMARCA4
SMARCE1
SMG7
SORBS2
SRC
SREK1
SRSF11
STK11
SUMO1
TAF1
TBP
TCAP
TERT
TFIP11
TOP1
TP53
TP53I3
TP53RK
TP73
TPR
TPT1
TRAF5
TRIM13
TRIM23
TRIM27
TRIM4
TRIM9
TSG101
UBB
UBC
UBE2A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2I
UBE2J2
UBE2K
UBE2L3
UBE2N
UBE2O
UBE2Q1
UBE2Q2
UBE2R2
UBE2S
UBE2U
UBE2Z
UBE3A
UBQLN4
UBTF
USP15
USP2
USP7
VEGFA
WRN
WT1
XBP1
XIAP
XPC
YY1AP1
ZNF133
ZNF420
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436 interacting genes:
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ABCA1
ABCC1
ACACA
ACAT2
ACE
ACIN1
AIP
AKAP8
AKT1
ALKBH5
ANP32B
APEX1
APOE
APP
AQP4
ARL6IP4
ARMCX3
ARNT
ARR3
ARRB2
ASIC3
ATF1
ATF2
ATG16L1
ATN1
ATP2B1
ATP5F1A
AUTS2
BCLAF1
BDP1
BEND7
BHLHE41
BID
BIRC6
BMS1
BRCA1
BRF1
BRMS1
C1orf109
C1orf35
C1R
CALM1
CALU
CANX
CARD9
CASP2
CASQ2
CAV1
CAV2
CCDC116
CCDC6
CD2BP2
CD5
CDC25B
CDC37
CDH1
CDK1
CDKN1A
CFDP1
CHD4
CHUK
CIRBP
CLASP2
CLNS1A
CLTB
COPS2
COPS3
COPS7A
CPSF6
CPSF7
CREB3L3
CREBBP
CREM
CSN1S1
CSN2
CSNK2B
CT45A1
CTDP1
CTNNA1
CTNNB1
CUX2
DAXX
DDIT3
DDX17
DDX21
DDX24
DDX3X
DDX54
DEK
DELEC1
DHX16
DHX38
DKC1
DNAJB2
DPF3
DTD1
DVL1
DVL3
ECD
EEF1B2
EEF1D
EGR1
EHMT2
EIF2B5
EIF2S1
EIF2S2
EIF3J
EIF4B
EIF4EBP1
EIF5
EIF5B
ERH
EXOSC9
F11R
F5
FAF1
FAM133A
FBXO28
FCHO1
FGF1
FGF2
FIBP
FIP1L1
FKBP3
FKBP4
FLG
FNBP4
FOS
FTSJ3
FXR1
GABRR1
GABRR2
GANAB
GAP43
GGA1
GMFB
GMNN
GPATCH2
GPATCH2L
GPI
GPN1
GRIN2A
GRIN2B
GSC2
GTF2A1
GTF2A1L
GTF2F1
GYS1
HCLS1
HDAC1
HDAC2
HDAC3
HDGFL2
HDLBP
HES6
HGS
HIF1A
HMGA1
HMGA2
HMOX2
HNRNPA2B1
HNRNPC
HNRNPDL
HNRNPL
HOXB7
HOXC4
HSF1
HSP90AA1
HSP90AB1
HSP90B1
HSPA4
HSPB8
HSPH1
HTATSF1
IFI16
IFRD1
IGF2R
IGFBP3
IL16
INF2
IRF2
IRS1
ITCH
IWS1
JADE2
JUN
KANK2
KDM1A
KEAP1
KIF1C
KIF24
KIF5C
KLF1
KPNA4
L1CAM
LARP1
LEO1
LGALS3
LHX3
LHX8
LHX9
LIG1
LRRC59
LSM14A
LTV1
MAF1
MAGEA11
MAK16
MAPK1
MAPK14
MAPT
MAX
MAZ
MCM2
MCM3
MDC1
MDM2
MEF2C
MEOX1
MEOX2
MFAP1
MGMT
MME
MPHOSPH10
MRPL38
MRPL4
MS4A1
MSH6
MTDH
MUS81
MYB
MYC
MYCN
MYF5
MYH9
NAF1
NAP1L1
NAP1L4
NCAPD2
NCL
NCOR1
NFKBIA
NFKBIB
NFYA
NKX2-5
NMD3
NMT1
NOL3
NOLC1
NOP56
NOP58
NPM1
NRF1
NUP98
NXF1
OCLN
OGDHL
OGT
OSBP
OTUB1
PACS1
PAFAH1B1
PAK1
PAX5
PAX6
PAX7
PDAP1
PDCD4
PDIA6
PGK1
PGR
PHF19
PIAS1
PIN1
PIN4
PIP4K2B
PLEKHO1
PML
PNN
POLR2A
POU6F2
PPAN
PPP1R1B
PPP1R2
PPP1R8
PRCC
PRKACB
PRNP
PRPF38A
PSEN2
PSIP1
PSMA3
PSMA4
PSME3IP1
PTEN
PTPA
PTPN1
PTPRC
PURB
RAD1
RAD51
RAD9A
RANGAP1
RBM10
RBM17
RBM33
RBM39
RBMX
REL
RELA
RGS19
RIOK1
RIOK2
RNF111
RNF7
RPL13
RPL5
RPL6
RPLP0
RPLP1
RPRD2
RPS18
RPS3
RPS6KB1
RRAD
RRP12
RRP1B
RRP9
RSF1
RSL1D1
SAFB
SAP30BP
SAT1
SCNN1A
SEPTIN2
SERBP1
SERPINF1
SF3A1
SF3B1
SF3B2
SFPQ
SHOX
SLC18A2
SLC4A1AP
SLIRP
SMARCC2
SNAI2
SNCA
SND1
SP1
SPATS2L
SPI1
SPIB
SPP1
SPTBN1
SQSTM1
SREK1
SRF
SRRM1
SRRM2
SRRT
SRSF10
SRSF11
SRSF2
SSB
SSRP1
STAC3
STMN1
STX1A
SUB1
SUDS3
SUGT1
SUPT5H
SUPT6H
SURF6
TCF7L2
TCOF1
TEPSIN
TFAP2A
TH
THAP1
THOC5
THRAP3
TLE5
TMOD3
TMPO
TNKS1BP1
TNP1
TOP1
TOP2A
TP53
TP63
TP73
TRIM41
TSPY1
TSPYL2
UBAC1
UBE2D3
UBE2R2
UBTF
USP24
USP48
USP7
UTP14A
UTP18
VAMP4
VDR
VHL
VTN
WAS
WDR44
WDR55
WEE1
XK
XKRY
XRCC1
XRCC4
XRCC5
XRCC6
XRN2
YBX1
YWHAB
YWHAQ
ZC3H13
ZC3H15
ZC3H8
ZFC3H1
ZHX1
ZNF177
ZNF440
ZNF558
ZNF559-ZNF177
ZNF670
ZRANB2
ZSCAN25
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Entrez ID |
4193 |
1457 |
HPRD ID |
01272 |
00277 |
Ensembl ID |
ENSG00000135679
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ENSG00000101266
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Uniprot IDs |
A0A0A8KB75
A7UKX7
A7UKX8
A7UKX9
G3XA89
Q00987
Q96DS0
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P68400
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PDB IDs |
1RV1
1T4E
1T4F
1YCR
1Z1M
2AXI
2C6A
2C6B
2F1Y
2FOP
2GV2
2HDP
2LZG
2M86
2MPS
2RUH
2VJE
2VJF
3EQS
3G03
3IUX
3IWY
3JZK
3JZR
3JZS
3LBK
3LBL
3LNJ
3LNZ
3MQS
3TJ2
3TPX
3TU1
3V3B
3VBG
3VZV
3W69
4DIJ
4ERE
4ERF
4HBM
4HFZ
4HG7
4JV7
4JV9
4JVE
4JVR
4JWR
4MDN
4MDQ
4OAS
4OBA
4OCC
4ODE
4ODF
4OGN
4OGT
4OGV
4OQ3
4QO4
4QOC
4UD7
4UE1
4UMN
4WT2
4XXB
4ZFI
4ZGK
4ZYC
4ZYF
4ZYI
5AFG
5C5A
5HMH
5HMI
5HMK
5J7F
5J7G
5LAV
5LAW
5LAY
5LAZ
5LN2
5MNJ
5OAI
5OC8
5SWK
5TRF
5UMM
5VK0
5WTS
5XXK
5Z02
5ZXF
6AAW
6GGN
6H22
6HFA
6I29
6I3S
6IM9
6KZU
6Q96
6Q9H
6Q9L
6Q9O
6SQO
6T2D
6T2E
6T2F
6Y4Q
7AD0
7AI0
7AI1
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1JWH
1NA7
1PJK
2PVR
2ZJW
3AMY
3AT2
3AT3
3AT4
3AXW
3BQC
3C13
3FWQ
3H30
3JUH
3MB6
3MB7
3NGA
3NSZ
3OWJ
3OWK
3OWL
3PE1
3PE2
3PE4
3Q04
3Q9W
3Q9X
3Q9Y
3Q9Z
3QA0
3R0T
3RPS
3TAX
3U4U
3U87
3U9C
3W8L
3WAR
3WIK
3WIL
3WOW
4DGL
4FBX
4GRB
4GUB
4GYW
4GYY
4GZ3
4IB5
4KWP
4MD7
4MD8
4MD9
4NH1
4RLL
4UB7
4UBA
5B0X
5CLP
5CQU
5CQW
5CS6
5CSH
5CSP
5CSV
5CT0
5CTP
5CU0
5CU2
5CU3
5CU4
5CU6
5CVF
5CVG
5CVH
5CX9
5H8B
5H8E
5H8G
5HGV
5KU8
5KWH
5M44
5M4C
5M4F
5M4I
5MMF
5MMR
5MO5
5MO6
5MO7
5MO8
5MOD
5MOE
5MOH
5MOT
5MOV
5MOW
5MP8
5MPJ
5N1V
5N9K
5N9L
5N9N
5NQC
5OMY
5ONI
5OQU
5ORH
5ORJ
5ORK
5OS7
5OS8
5OSL
5OSP
5OSR
5OSU
5OSZ
5OT5
5OT6
5OTD
5OTH
5OTI
5OTL
5OTO
5OTP
5OTQ
5OTR
5OTS
5OTY
5OTZ
5OUE
5OUL
5OUM
5OUU
5OWH
5OWL
5OYF
5T1H
5VIE
5VIF
5ZN0
5ZN1
5ZN2
5ZN3
5ZN4
5ZN5
6A1C
6E37
6EHK
6EHU
6EII
6FVF
6FVG
6GIH
6GMD
6HBN
6HME
6HNW
6HNY
6HOP
6HOQ
6HOR
6HOT
6HOU
6JWA
6L1Z
6L21
6L22
6L24
6Q38
6Q4Q
6QY7
6RB1
6RCB
6RCM
6RFE
6RFF
6SPW
6SPX
6TEI
6TLL
6TLO
6TLP
6TLR
6TLS
6TLU
6TLV
6TLW
6YPG
6YPH
6YPJ
6YPK
6YPN
6YUL
6YUM
6Z83
6Z84
7A49
7A4B
7A4C
7B8H
7B8I
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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