PLPP6 and PDZK1IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	PDZK1IP1
Description		phospholipid phosphatase 6	PDZK1 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways		Cholesterol biosynthesis
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17
Entrez ID		403313	10158
HPRD ID		17397	06211
Ensembl ID		ENSG00000205808	ENSG00000162366
Uniprot IDs		Q8IY26	Q13113
PDB IDs
Enriched GO Terms of Interacting Partners?
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