PLPP6 and PHACTR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	PHACTR3
Description		phospholipid phosphatase 6	phosphatase and actin regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Nucleoplasm Nuclear Matrix
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity
Pathways		Cholesterol biosynthesis
Drugs
Diseases
GWAS			Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Schizophrenia ( 30285260)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	10 interacting genes: CAPNS2 CYB5B EEF1G MAPK6 PLPP6 PPP1CA PPP1CB TAB1 UBIAD1 UBL5
Entrez ID		403313	116154
HPRD ID		17397	10571
Ensembl ID		ENSG00000205808	ENSG00000087495
Uniprot IDs		Q8IY26	B7Z339 Q96KR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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