PLPP6 and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLPP6	IL10RA
Description		phospholipid phosphatase 6	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Cholesterol Biosynthetic Process Phospholipid Dephosphorylation	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis
Pathways		Cholesterol biosynthesis	Interleukin-10 signaling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR	22 interacting genes: BTRC C1QL4 CDS2 CMTM3 DRD2 HACD1 IL10 IL10RB JAK1 KMT2A MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		403313	3587
HPRD ID		17397	00911
Ensembl ID		ENSG00000205808	ENSG00000110324
Uniprot IDs		Q8IY26	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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