PDZK1IP1 and EMC6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDZK1IP1	EMC6
Description		PDZK1 interacting protein 1	ER membrane protein complex subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Extracellular Exosome	Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane EMC Complex Integral Component Of Omegasome Membrane
	Molecular Function	Protein Binding	Protein Binding Membrane Insertase Activity
	Biological Process		Autophagosome Assembly Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17	17 interacting genes: AQP6 AQP9 CD79A CREB3 EBP ERGIC3 FAM209A MFSD14B MMD MUC1 PDZK1IP1 SLC10A6 SLC39A2 SLC7A1 TLCD4 TMEM14B TMEM237
Entrez ID		10158	83460
HPRD ID		06211	14529
Ensembl ID		ENSG00000162366	ENSG00000127774
Uniprot IDs		Q13113	Q9BV81
PDB IDs			6WW7 6Z3W 7ADO 7ADP
Enriched GO Terms of Interacting Partners?
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