TNPO1 and PABPN1

Number of citations of the paper that reports this interaction (PubMedID 10688363)
30

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TNPO1	PABPN1
Description		transportin 1	poly(A) binding protein nuclear 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cilium Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	RNA Binding Protein Binding RNA Polymerase Binding
	Biological Process	Protein Import Into Nucleus	MAPK Cascade RNA Processing MRNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity
Pathways		Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport Postmitotic nuclear pore complex (NPC) reformation	Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Factor VIII levels ( 30586737) Height ( 31562340) Hemoglobin ( 32888494) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean platelet volume ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 28957414) Serum albumin level ( 29403010) vWF levels ( 30586737)	Body mass index ( 26865924) Lymphocyte counts ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		18 interacting genes: ELAVL1 H2BC21 H3-4 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19 ULK2	16 interacting genes: AKAP6 CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 MYCBP2 OGT PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ
Entrez ID		3842	8106
HPRD ID		04210	03787
Ensembl ID		ENSG00000083312	ENSG00000100836
Uniprot IDs		A0A024RAM0 Q92973	Q86U42
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ 4OO6 5J3V 5TQC 5YVG 5YVH 5YVI 7CYL	3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?
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