PABPN1 and AKAP6

		PABPN1	AKAP6
Description		poly(A) binding protein nuclear 1	A-kinase anchoring protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex	Nuclear Envelope Cytoplasm Caveola Junctional Sarcoplasmic Reticulum Membrane Intercalated Disc Sarcoplasmic Reticulum T-tubule Nuclear Membrane Calcium Channel Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding RNA Polymerase Binding	Protein Binding Adenylate Cyclase Binding Protein Kinase A Regulatory Subunit Binding Protein-membrane Adaptor Activity Transmembrane Transporter Binding Protein Kinase A Binding Molecular Adaptor Activity
	Biological Process	MAPK Cascade RNA Processing MRNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity	Action Potential Protein Targeting Regulation Of Protein Kinase A Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum CAMP-mediated Signaling Positive Regulation Of Cell Growth Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Membrane Repolarization Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To CAMP Cellular Response To Cytokine Stimulus Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Body mass index ( 26865924) Lymphocyte counts ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Anorexia nervosa ( 21079607) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 29273806) Atrial fibrillation ( 30061737 29892015) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index and systole blood pressure (pairwise) ( 33619380) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Coffee consumption ( 31046077) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 25644384) Creatine kinase levels ( 29403010) Diisocyanate-induced asthma ( 25918132) Economic and political preferences (environmentalism) ( 22566634) Fasting blood insulin (BMI interaction) ( 22581228) General cognitive ability ( 29844566) Glioma ( 28346443) HDL cholesterol levels ( 32203549) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Non-glioblastoma glioma ( 28346443) Photic sneeze reflex ( 27182965) PR interval ( 32439900) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Type 2 diabetes ( 30297969) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Walking pace ( 33128006)
Interacting Genes		16 interacting genes: AKAP6 CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 MYCBP2 OGT PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	19 interacting genes: BIRC5 CALM1 CDC5L DISC1 DTNBP1 FUT3 GEMIN2 MAGEA6 PABPN1 PDE4D PGC PPP2CA PRKAR2A PTPRM RYR1 RYR2 SLC8A1 SPTSSA SSTR1
Entrez ID		8106	9472
HPRD ID		03787	05257
Ensembl ID		ENSG00000100836	ENSG00000151320
Uniprot IDs		Q86U42	B2RP22 Q13023
PDB IDs		3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?
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