TNPO1 and ULK2

Number of citations of the paper that reports this interaction (PubMedID 26052940)
1

Data Source:
BioGRID (pull down)

		TNPO1	ULK2
Description		transportin 1	unc-51 like autophagy activating kinase 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cilium Extracellular Exosome	Cytoplasm Cytoplasmic Vesicle Membrane Phagophore Assembly Site Membrane
	Molecular Function	RNA Binding Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Protein Import Into Nucleus	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Signal Transduction Peptidyl-serine Phosphorylation Piecemeal Microautophagy Of The Nucleus Response To Starvation Late Nucleophagy Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension Reticulophagy Positive Regulation By Symbiont Of Host Autophagy
Pathways		Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport Postmitotic nuclear pore complex (NPC) reformation
Drugs			Fostamatinib
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Factor VIII levels ( 30586737) Height ( 31562340) Hemoglobin ( 32888494) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 27863252) Mean platelet volume ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 28957414) Serum albumin level ( 29403010) vWF levels ( 30586737)
Interacting Genes		18 interacting genes: ELAVL1 H2BC21 H3-4 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19 ULK2	16 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 RAI1 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32
Entrez ID		3842	9706
HPRD ID		04210	10556
Ensembl ID		ENSG00000083312	ENSG00000083290
Uniprot IDs		A0A024RAM0 Q92973	Q8IYT8
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ 4OO6 5J3V 5TQC 5YVG 5YVH 5YVI 7CYL	6QAT 6QAU 6QAV 6YID
Enriched GO Terms of Interacting Partners?
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