ARL4D and EML4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL4D	EML4
Description		ADP ribosylation factor like GTPase 4D	EMAP like 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Plasma Membrane	Cytoplasm Microtubule Organizing Center Cytosol Microtubule Membrane Midbody Mitotic Spindle
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Molecular_function Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Mitotic Metaphase Plate Congression Attachment Of Spindle Microtubules To Kinetochore Cell Division
Pathways			EML4 and NUDC in mitotic spindle formation ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1) ( 30061609) Metabolite levels ( 23823483) PR interval ( 32439900) Type 2 diabetes ( 31118516)
Interacting Genes		22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119	7 interacting genes: ARIH2 ARL4D MTCH1 NEK6 NEK7 TUBA1B TUBB
Entrez ID		379	27436
HPRD ID		02842	06310
Ensembl ID		ENSG00000175906	ENSG00000143924
Uniprot IDs		P49703	B5MBZ0 Q9HC35
PDB IDs			4CGC
Enriched GO Terms of Interacting Partners?
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