EML4 and ARL4D

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EML4	ARL4D
Description		EMAP like 4	ADP ribosylation factor like GTPase 4D
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytosol Microtubule Membrane Midbody Mitotic Spindle	Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	Molecular_function Protein Binding Microtubule Binding Alpha-tubulin Binding Beta-tubulin Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Mitotic Metaphase Plate Congression Attachment Of Spindle Microtubules To Kinetochore Cell Division	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport
Pathways		EML4 and NUDC in mitotic spindle formation ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Hip circumference adjusted for BMI ( 34021172) Lung function (FEV1) ( 30061609) Metabolite levels ( 23823483) PR interval ( 32439900) Type 2 diabetes ( 31118516)
Interacting Genes		7 interacting genes: ARIH2 ARL4D MTCH1 NEK6 NEK7 TUBA1B TUBB	22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119
Entrez ID		27436	379
HPRD ID		06310	02842
Ensembl ID		ENSG00000143924	ENSG00000175906
Uniprot IDs		B5MBZ0 Q9HC35	P49703
PDB IDs		4CGC
Enriched GO Terms of Interacting Partners?
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