ITK and LCP2

  • Number of citations of the paper that reports this interaction (PubMedID 10636929)
  • 90
  • Data Source:
  • HPRD (in vitro, in vivo)

ITK

LCP2

Description IL2 inducible T cell kinase lymphocyte cytosolic protein 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025)
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes 35 interacting genes: BLNK BMX BTK CBL CD28 DOK1 EGFR ERBB2 ERBB3 ERBB4 FASLG FGFR1 FYN GAB1 GRB2 HNRNPK IKBKG KHDRBS1 KPNA2 LAT LCK LCP2 MET PDGFRB PLCG1 PLCG2 PPIA SH2D2A SMAD4 SMURF1 SOCS1 SPRR2A SRC TGFBR1 WAS 50 interacting genes: APP BLNK CBL CD22 CLNK EGFR ELOVL6 ERBB2 ERBB3 ERBB4 FXR2 FYB1 FYN GALNT10 GOLGA2 GRAP2 GRB2 HCK ITK LARP1 LAT LCK LMNA LNX1 LYN MAP4K1 NCK1 NCK2 PAG1 PJA1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SH3RF1 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAE YWHAZ ZAP70
Entrez ID 3702 3937
HPRD ID 01746 03362
Ensembl ID ENSG00000113263 ENSG00000043462
Uniprot IDs Q08881 Q13094
PDB IDs 1SM2 1SNU 1SNX 2E6I 2LMJ 2YUQ 3MIY 3MJ1 3MJ2 3QGW 3QGY 3T9T 3V5J 3V5L 3V8T 3V8W 4HCT 4HCU 4HCV 4KIO 4L7S 4M0Y 4M0Z 4M12 4M13 4M14 4M15 4MF0 4MF1 4PP9 4PPA 4PPB 4PPC 4PQN 4QD6 4RFM 1H3H 1YWO 2EAP 2ROR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?