AQP5 and GLRX

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		AQP5	GLRX
Description		aquaporin 5	glutaredoxin
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basal Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Extracellular Exosome	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Water Channel Activity Identical Protein Binding	Glutathione-disulfide Reductase (NADPH) Activity Protein Binding Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Water Transport Carbon Dioxide Transport Pancreatic Juice Secretion Odontogenesis Saliva Secretion Camera-type Eye Morphogenesis Protein Homotetramerization Transmembrane Transport Cellular Hypotonic Response	Nucleobase-containing Small Molecule Interconversion Positive Regulation Of Membrane Potential Protein Deglutathionylation Cellular Oxidant Detoxification Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Passive transport by Aquaporins	Interconversion of nucleotide di- and triphosphates
Drugs			Glutathione
Diseases
GWAS		Allergic rhinitis ( 30013184) Asthma ( 32296059)	hemolysis of donated blood (oxidative) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		9 interacting genes: CREB3 GLRX HNRNPK KRT31 KRT40 MDFI NOTCH2NLA TUBA1C WNT2	8 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1 TRIM62
Entrez ID		362	2745
HPRD ID		02706	02707
Ensembl ID		ENSG00000161798	ENSG00000173221
Uniprot IDs		P55064	A0A024RAM2 P35754
PDB IDs		3D9S 5C5X 5DYE	1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
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