GLRX and MMP23B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GLRX	MMP23B
Description		glutaredoxin	matrix metallopeptidase 23B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Glutathione-disulfide Reductase (NADPH) Activity Protein Binding Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity	Metalloendopeptidase Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Nucleobase-containing Small Molecule Interconversion Positive Regulation Of Membrane Potential Protein Deglutathionylation Cellular Oxidant Detoxification Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Reproduction Proteolysis Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Glutathione	Marimastat
Diseases
GWAS		hemolysis of donated blood (oxidative) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Body mass index ( 26426971)
Interacting Genes		8 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1 TRIM62	3 interacting genes: GLRX MTHFR SRPK2
Entrez ID		2745	8510
HPRD ID		02707	04503
Ensembl ID		ENSG00000173221	ENSG00000189409
Uniprot IDs		A0A024RAM2 P35754	O75900
PDB IDs		1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
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