GLRX

Description		glutaredoxin
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GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome
	Molecular Function	Glutathione-disulfide Reductase (NADPH) Activity Protein Binding Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Nucleobase-containing Small Molecule Interconversion Positive Regulation Of Membrane Potential Protein Deglutathionylation Cellular Oxidant Detoxification Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Glutathione
Diseases
GWAS		hemolysis of donated blood (oxidative) ( 34014839) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Metabolite levels ( 23823483) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		8 interacting genes: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1 TRIM62
Entrez ID		2745
HPRD ID		02707
Ensembl ID		ENSG00000173221
Uniprot IDs		A0A024RAM2 P35754
PDB IDs		1B4Q 1JHB 4RQR
Enriched GO Terms of Interacting Partners?
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