ACER2 and MPP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ACER2	MPP1
Description		alkaline ceramidase 2	MAGUK p55 scaffold protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Golgi Membrane	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite
	Molecular Function	N-acylsphingosine Amidohydrolase Activity Metal Ion Binding Dihydroceramidase Activity Ceramidase Activity	Guanylate Kinase Activity Protein Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Regulation Of Autophagy Positive Regulation Of Cell Death Sphingolipid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Response To Retinoic Acid Negative Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Apoptotic Process Sphingosine Biosynthetic Process Ceramide Catabolic Process Negative Regulation Of Protein Glycosylation In Golgi	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis
Pathways		Sphingolipid de novo biosynthesis	Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS			Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		1 interacting genes: MPP1	46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639
Entrez ID		340485	4354
HPRD ID		16512	02370
Ensembl ID		ENSG00000177076	ENSG00000130830
Uniprot IDs		B3KVV5 Q5QJU3	B4E325 Q00013
PDB IDs			2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?
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