HSPE1 and GBP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HSPE1	GBP2
Description		heat shock protein family E (Hsp10) member 1	guanylate binding protein 2
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Membrane Extracellular Exosome	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding ATP Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Osteoblast Differentiation Protein Folding Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		RHOG GTPase cycle	Interferon gamma signaling Interferon alpha/beta signaling
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Serum metabolite levels ( 33031748)
Interacting Genes		16 interacting genes: ALDH2 APLP1 CASP3 CRMP1 EEF1A1 ERG28 GBP2 HSPD1 LRIF1 NTAQ1 SAT1 SELENOM STK3 TLE1 UNC119 ZHX1	23 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LRRC8B LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG
Entrez ID		3336	2634
HPRD ID		02535	02682
Ensembl ID		ENSG00000115541	ENSG00000162645
Uniprot IDs		A0A384N6A4 P61604	P32456 Q8TCE5
PDB IDs		4PJ1 6HT7 6MRC 6MRD	6VKJ
Enriched GO Terms of Interacting Partners?
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