GBP2 and SERPINB9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GBP2	SERPINB9
Description		guanylate binding protein 2	serpin family B member 9
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Extracellular Space Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Protein Homodimerization Activity	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Mast Cell Mediated Immunity Apoptotic Process Immune Response Response To Bacterium Positive Regulation Of Gene Expression Negative Regulation Of Endopeptidase Activity Negative Regulation By Symbiont Of Host Apoptotic Process Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Estrogen Stimulus
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs			Raloxifene
Diseases
GWAS		Serum metabolite levels ( 33031748)	Left ventricular global circumferential strain ( 33495596) Plateletcrit ( 32888494) Vitiligo ( 27723757)
Interacting Genes		23 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LRRC8B LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	28 interacting genes: BRD7 CASP1 CASP4 CCDC90B COPS6 CRMP1 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 GZMB IGSF21 LRIF1 MED31 PLEKHM1 PRPF40A RBM48 SETDB1 TLE1 TP53 TRAF5 TUBB2A UBR1 UNC119 XRCC6 ZHX1
Entrez ID		2634	5272
HPRD ID		02682	03480
Ensembl ID		ENSG00000162645	ENSG00000170542
Uniprot IDs		P32456 Q8TCE5	A0A024QZT4 P50453
PDB IDs		6VKJ
Enriched GO Terms of Interacting Partners?
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