GBP2 and BTBD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GBP2	BTBD2
Description		guanylate binding protein 2	BTB domain containing 2
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	P-body Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Neurogenesis
Pathways		Interferon gamma signaling Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		23 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LRRC8B LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG	37 interacting genes: BRD7 CCDC90B CCNC CDK2 CINP COPS6 CRMP1 CUL3 DPPA4 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 IGSF21 KPNA2 MLH1 NGB NTAQ1 OSGIN1 PSMD5 PTN RBM48 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B ZYG11B
Entrez ID		2634	55643
HPRD ID		02682	12252
Ensembl ID		ENSG00000162645	ENSG00000133243
Uniprot IDs		P32456 Q8TCE5	Q9BX70
PDB IDs		6VKJ	3NO8
Enriched GO Terms of Interacting Partners?
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